James J Pestka Selected Research

3-acetyldeoxynivalenol

8/2016	Modeling the emetic potencies of food-borne trichothecenes by benchmark dose methodology.
4/2014	Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol.
1/2013	Comparison of emetic potencies of the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol.

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James J Pestka Research Topics

Disease

22	Inflammation (Inflammations) 04/2022 - 10/2002
17	Glomerulonephritis 01/2021 - 02/2002
10	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 04/2010
10	IGA Glomerulonephritis (IGA Nephropathy) 04/2010 - 02/2002
8	Vomiting 01/2017 - 01/2005
7	Body Weight (Weight, Body) 09/2013 - 12/2004
6	Anorexia 10/2015 - 01/2010
5	Pneumonia (Pneumonitis) 04/2022 - 07/2008
5	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2021 - 01/2015
5	Gastroenteritis 04/2016 - 01/2005
5	Weight Gain 07/2015 - 10/2009
4	Tertiary Lymphoid Structures 01/2021 - 01/2015
4	Infections 01/2010 - 08/2006
3	Foodborne Diseases 01/2015 - 01/2013
3	Reoviridae Infections 04/2008 - 08/2006
2	Cadaver (Cadavers) 11/2020 - 01/2020
2	Necrosis 11/2020 - 01/2010
2	Neoplasms (Cancer) 02/2020 - 05/2008
2	Nephritis 01/2020 - 01/2019
2	Proteinuria 01/2016 - 01/2014
2	Lupus Nephritis 01/2014 - 04/2010
2	Hemorrhage 07/2010 - 01/2004
2	Shock 01/2010 - 03/2003
1	Vasculitis (Vasculitides) 11/2020
1	Celiac Disease (Celiac Sprue) 11/2020
1	Systemic Scleroderma (Systemic Sclerosis) 11/2020
1	Myositis (Idiopathic Inflammatory Myopathies) 11/2020
1	Autoimmune Hepatitis 11/2020
1	Rheumatoid Arthritis 11/2020
1	Colitis 02/2020
1	Carcinogenesis 02/2020

Drug/Important Bio-Agent (IBA)

23	deoxynivalenolIBA 01/2017 - 10/2002
21	MycotoxinsIBA 01/2017 - 10/2002
15	trichotheceneIBA 04/2016 - 10/2002
14	Docosahexaenoic AcidsIBA 04/2022 - 06/2004
13	Silicon Dioxide (Silica)FDA LinkGeneric 01/2021 - 01/2015
10	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 03/2021 - 10/2006
10	CytokinesIBA 01/2021 - 03/2003
9	AutoantibodiesIBA 01/2021 - 01/2014
7	Interleukin-6 (Interleukin 6)IBA 01/2010 - 12/2003
7	Immunoglobulin A (IgA)IBA 01/2010 - 04/2003
6	InterferonsIBA 01/2021 - 01/2020
6	Messenger RNA (mRNA)IBA 02/2020 - 12/2004
6	Hormones (Hormone)IBA 01/2017 - 05/2013
6	EmeticsIBA 04/2016 - 01/2005
5	Fish OilsIBA 01/2021 - 02/2002
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2008
4	ChemokinesIBA 01/2021 - 01/2019
4	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2021 - 04/2003
4	Immunoglobulin G (IgG)IBA 01/2021 - 08/2006
4	T-2 Toxin (T 2 Toxin)IBA 08/2016 - 08/2006
4	TrichothecenesIBA 10/2015 - 04/2010
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 01/2008
3	fusarenon-XIBA 08/2016 - 01/2013
3	15-acetyldeoxynivalenolIBA 08/2016 - 01/2013
3	3-acetyldeoxynivalenolIBA 08/2016 - 01/2013
3	nivalenolIBA 08/2016 - 01/2013
3	Peptide Hormones (Polypeptide Hormones)IBA 04/2016 - 12/2012
3	satratoxin GIBA 08/2012 - 01/2004
3	Eicosapentaenoic AcidIBA 04/2010 - 06/2004
3	Immunoglobulins (Immunoglobulin)IBA 04/2008 - 02/2002
2	dehydroacetic acid (DHAS)IBA 04/2022 - 01/2016
2	docosahexaenoylascorbic acid (DHA-As)IBA 04/2022 - 03/2021
2	InflammasomesIBA 01/2021 - 01/2020
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2014
2	CalciumIBA 01/2021 - 02/2020
2	titanium dioxide (Titania)FDA Link 01/2021 - 09/2013
2	AutoantigensIBA 01/2021 - 11/2020
2	peptide YY (3-36)IBA 01/2017 - 05/2013
2	HT-2 toxinIBA 08/2016 - 04/2016
2	Serotonin (5 Hydroxytryptamine)IBA 04/2016 - 05/2013
2	Neurotransmitter Agents (Neurotransmitter)IBA 04/2016 - 05/2013
2	Appetite Depressants (Anorectics)IBA 11/2014 - 07/2013
2	Cholecystokinin (Pancreozymin)IBA 04/2014 - 05/2013
2	LipidsIBA 01/2014 - 12/2003
2	neuropeptide Y2 receptorIBA 05/2013 - 12/2012
2	AcidsIBA 02/2010 - 01/2008
2	LipopolysaccharidesIBA 08/2007 - 03/2003
1	CholesterolIBA 01/2021
1	AsbestosIBA 01/2021
1	AluminumIBA 01/2021
1	ProteomeIBA 01/2021
1	SaltsIBA 01/2021
1	Carbon Nanotubes (Carbon Nanotube)IBA 01/2021
1	Uric Acid (Urate)IBA 01/2021
1	VimentinIBA 11/2020
1	Type I DNA Topoisomerases (Topoisomerase I)IBA 11/2020
1	CollagenIBA 11/2020
1	Fibrinogen (Factor I)FDA Link 11/2020
1	Fibronectins (Fibronectin)IBA 11/2020
1	fodrinIBA 11/2020
1	AzoxymethaneIBA 02/2020
1	Vitamin D FDA LinkGeneric 02/2020
1	Dextrans (Dextran)FDA Link 02/2020
1	MicronutrientsIBA 02/2020
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 02/2020
1	StaurosporineIBA 01/2020
1	NigericinIBA 01/2020

Therapy/Procedure

3	Oral Administration 04/2016 - 01/2013
1	Duration of Therapy 03/2021